NIH-funded research R01 grant

Helping women cope with depression after losing a baby

Official title: IPT for major depression following perinatal loss

Funded at Michigan State University · NIH-10892190 · Data updated 2026-11-12

This study is looking to help women who have gone through the heartbreak of losing a baby and are dealing with depression by testing a special therapy designed just for them, which focuses on their unique feelings and challenges.

More Depression research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMichigan State University
NIH-funded
Lab location1 site (East Lansing, United States)
Project startAugust 7, 2020
Project endJuly 31, 2026
Funding year2024
Award (this year)$623,828
NIH project number5R01HD100471-05
Project IDNIH-10892190 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who have recently experienced perinatal loss and are experiencing symptoms of major depressive disorder.

Less likely to help

Patients who have not experienced perinatal loss or those who do not have symptoms of depression may not benefit from this research.

What this research studies

This research focuses on women who have experienced perinatal loss, such as miscarriage or stillbirth, and are suffering from major depressive disorder (MDD). It aims to develop and test a structured treatment using interpersonal psychotherapy (IPT) principles tailored specifically for this population. The approach addresses the unique emotional challenges faced by these women, including grief, social support, and feelings of guilt. By providing a manualized treatment that can be used by various healthcare providers, the research seeks to improve mental health outcomes for these women.

Why it matters

Potential benefit: If successful, this research could provide effective therapeutic options for women struggling with depression after perinatal loss, potentially improving their mental health and quality of life.

How similar studies have gone: Previous pilot studies have shown promise in using IPT for treating depression in this specific context, indicating a potential for success in this larger research effort.

Where this research is happening

  • Michigan State University
    East Lansing, United States
    Active

Researchers

  • Principal investigator: Johnson, Jennifer E — Michigan State University
  • Study coordinator: Johnson, Jennifer E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.