Helping women at high risk of breast cancer manage their health better
Official title: Developing a Patient Navigation Intervention to Improve Risk Management among Women at High Risk of Breast Cancer
Funded at Ohio State University · NIH-10767979 · Data updated 2026-11-12
This study is creating a helpful program for women at high risk of breast cancer to make it easier for them to understand their options for prevention and care, so they can make informed choices and get the support they need.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | February 1, 2023 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $174,874 |
| NIH project number | 5R21CA271070-02 |
| Project ID | NIH-10767979 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women with a family history or genetic predisposition to breast cancer who are currently not utilizing recommended risk management options.
✕Less likely to help
Patients who do not have a family history or genetic predisposition to breast cancer may not receive benefit from this research.
What this research studies
This research aims to develop a patient navigation intervention specifically designed for women who are at high risk of breast cancer due to family history or genetic factors. The approach focuses on improving access to risk management options, such as surveillance routines, preventive surgeries, and medications, which are often underutilized. By providing personalized risk information and connecting women with healthcare providers, the intervention seeks to support informed decision-making and facilitate the adoption of effective risk management behaviors. The study will also identify barriers that prevent women from accessing these critical health services.
Why it matters
Potential benefit: If successful, this research could significantly improve breast cancer risk management and early detection for high-risk women.
How similar studies have gone: Previous research has shown success in similar interventions aimed at improving health management behaviors among high-risk populations.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Padamsee, Tasleem J — Ohio State University
- Study coordinator: Padamsee, Tasleem J
Related research
Other NIH-funded projects on the same topics.
-
Improving Breast Cancer Guideline Adherence in Nigeria
Aimed at helping doctors in Nigeria follow international guideline-based breast cancer care to improve outcomes for women with breast cancer.
-
Genomic study to understand how genetics and epigenetics shape triple-negative breast cancer in African ancestry
This study looks at how inherited genes and gene activity affect triple-negative breast cancer in people of African ancestry to better understand why outcomes can be worse.
-
Translational breast cancer research to improve treatment options
A comprehensive program at Baylor College of Medicine is focusing on breast cancer; researchers will advance targeted therapies and biomarkers to help patients with aggressive or hard-to-treat forms.
-
Cancer Pain Management for Asian American Breast Cancer Survivors with Depressive Symptoms
A technology-based program helps Asian American breast cancer survivors with depressive symptoms manage chronic pain more effectively from home using a web app and mobile tools.
-
Co-Targeting IL-6 and CDK4/6 to Prevent TNBC in Women Veterans
A study aims to block two cancer-promoting pathways (IL-6 and CDK4/6) to prevent or reduce progression of triple-negative breast cancer in women veterans.
-
Gut bacteria and metabolites linked to breast density and cancer risk
A small, patient-friendly study will explore whether gut bacteria and their byproducts are connected to high breast density, which can raise cancer risk and make screening less accurate.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.