Helping Ugandan couples choose HIV prevention for women
Improving Choice and Use of Biomedical HIV Prevention for Women in Uganda: A Couples-Based Approach
A couples-based decision tool to help women in Uganda and their partners pick the HIV prevention option that best fits their needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-11383027 on NIH RePORTER |
What this research studies
You and your partner would be invited to use a paper-based decision tool called CUPID while choosing between HIV prevention options offered locally, such as long-acting injectable cabotegravir, the dapivirine vaginal ring, or daily oral PrEP. Peer PrEP ambassadors will introduce the tool in community or clinic settings and guide couples through trade-offs like how discreet each method is, how often it must be used, and how it might fit your life. The project will look at whether this couples approach helps women start and continue using the option they choose and will study how the tool works when used in real clinics. If you take part, researchers may follow you over time to learn what supports women's choices and consistent use of prevention.
Who could benefit from this research
Good fit: Women in Uganda who are eligible for PrEP and their male partners, especially those considering which biomedical prevention option to use, are ideal candidates.
Not a fit: People living with HIV (who need treatment rather than prevention) and individuals outside the study locations in Uganda are unlikely to benefit from participating.
Why it matters
Potential benefit: Could help women and their partners choose and stick with the HIV prevention option that fits their life, potentially lowering HIV risk.
How similar studies have performed: Multiple PrEP products like cabotegravir and the dapivirine ring have shown prevention benefit in trials but adherence and real-world use remain challenging, and couples-based or shared-decision approaches have shown promise though this specific tool is a newer implementation.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Minnis, Alexandra M — Research Triangle Institute
- Study coordinator: Minnis, Alexandra M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.