Helping the Brain Control Blood Sugar in Type 2 Diabetes
Restoring Central Regulation of Glucose Production in Type 2 Diabetes
This work explores how the brain can better manage blood sugar levels in people with type 2 diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11088170 on NIH RePORTER |
What this research studies
Our bodies naturally produce glucose, which is important for energy, but too much can cause problems in type 2 diabetes. We are learning that signals from the brain play a key role in controlling how much glucose the body makes. This project looks at how certain brain pathways, which are often impaired in type 2 diabetes, might be restored to help regulate blood sugar. We are particularly interested in whether lowering fat levels in the body can help the brain regain its ability to control glucose production. This understanding could lead to new ways to manage type 2 diabetes.
Who could benefit from this research
Good fit: Ideal candidates for related future studies would likely be adults diagnosed with type 2 diabetes.
Not a fit: Patients without type 2 diabetes or those with other forms of diabetes may not directly benefit from this specific research focus.
Why it matters
Potential benefit: If successful, this work could lead to new treatments that help the brain more effectively regulate blood sugar, potentially improving outcomes for people with type 2 diabetes.
How similar studies have performed: Our group's ongoing work suggests that central nervous system signals are important in regulating glucose production, building on existing knowledge in the field.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Hawkins, Meredith a — Albert Einstein College of Medicine
- Study coordinator: Hawkins, Meredith a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.