Helping teens make better choices to avoid alcohol and drug problems

Improving Decision Making to Prevent Substance Misuse among Adolescents

NIH-funded research Wayne State University · NIH-11287166

This project tries a computer-based working memory training program for teens—especially those from poorer neighborhoods—to help them make less impulsive choices and lower the chance of starting or increasing alcohol and drug use.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWayne State University NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-11287166 on NIH RePORTER

What this research studies

You would use a computer-based working memory training program that aims to strengthen the mental skills used in decision making. Researchers will look at whether the training reduces a tendency to pick immediate rewards over larger later rewards (called delay discounting). The work focuses on adolescents who experienced early life adversity or live in disadvantaged neighborhoods and who face higher risk of substance use. The team aims to make the training practical to deliver in community settings so more teens can access it.

Who could benefit from this research

Good fit: Ideal candidates are adolescents who have experienced early adversity or live in poorer neighborhoods and who are at risk of starting or escalating substance use.

Not a fit: Teens with long-standing, severe substance use disorders or those for whom computer-based cognitive training is not appropriate may not receive benefit from this intervention.

Why it matters

Potential benefit: If successful, this could help teens make less impulsive decisions and lower their risk of developing or worsening alcohol and drug problems.

How similar studies have performed: Early pilot work and some recent studies suggest working memory training can change decision-making measures like delay discounting, but evidence for preventing teen substance use is still limited.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.