NIH-funded research R01 grant

Helping South African children and teens build stronger emotion control and resilience

Official title: Resilient Emotion Regulation Development in a South African Birth Cohort

Funded at Columbia Univ New York Morningside · NIH-11138645 · Data updated 2026-11-12

This project looks at how supportive experiences help children and teens in South Africa manage their emotions and develop stronger, more resilient brains.

More Emotion Regulation research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia Univ New York Morningside
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 2, 2023
Project endJune 30, 2028
Funding year2025
Award (this year)$558,251
NIH project number5R01MH130578-03
Project IDNIH-11138645 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are children and adolescents (and their caregivers) from the Cape Town birth cohort, especially those who experienced early-life adversity.

Less likely to help

People who are not part of the Cape Town cohort, live far from the study sites, or are seeking immediate clinical treatment may not experience direct benefit from this research.

What this research studies

You would be part of a long-term birth cohort in Cape Town where researchers follow children from before birth into adolescence. The team uses brain scans, detailed behavior testing, and thorough information about family and neighborhood experiences, and they work with the local community to guide the research. Advanced data analysis ties protective factors—like caregiving, schooling, or social supports—to patterns of brain development and emotion control. The goal is to explain why some young people do well despite early hardship and to suggest ways communities can better support youth mental health.

Why it matters

Potential benefit: If successful, this work could point to practical supports and programs that help children avoid mental health problems and improve emotional coping.

How similar studies have gone: Previous studies in high-income countries have linked protective experiences to better emotion regulation, but applying multimodal brain imaging and community-guided methods in a South African birth cohort is relatively new.

Where this research is happening

  • Columbia Univ New York Morningside
    New York, United States
    Active

Researchers

  • Principal investigator: Tottenham, Nim — Columbia Univ New York Morningside
  • Study coordinator: Tottenham, Nim

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.