NIH-funded research NIH-funded research

Helping primary care patients on opioids feel less lonely to prevent misuse.

Official title: Addressing Loneliness in Primary Care Patients on Chronic Opioids to Prevent Opioid Misuse

Funded at University of Washington · NIH-11052606 · Data updated 2026-11-12

This study is looking for people with chronic pain who take opioids and often feel lonely, to see if special programs can help them connect with others and feel better, which might also lower the chances of misusing their medication.

More Primary Care research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Washington
NIH-funded
Lab location1 site (Seattle, United States)
Project startMay 15, 2023
Project endMarch 31, 2026
Funding year2025
Award (this year)$194,375
NIH project number5R34DA058325-03
Project IDNIH-11052606 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are primary care patients who are on chronic opioid therapy and experiencing feelings of loneliness.

Less likely to help

Patients who are not on chronic opioids or do not experience loneliness may not benefit from this research.

What this research studies

This research focuses on patients with chronic pain who are prescribed opioids and often experience loneliness, which can lead to negative health outcomes and increased risk of opioid misuse. The study aims to develop and test interventions that address loneliness through cognitive behavioral therapy and social navigation, helping patients improve their social connections and mental well-being. By implementing these interventions in primary care settings, the research seeks to create a supportive environment that reduces the likelihood of opioid misuse. Participants will be involved in a pilot trial to evaluate the effectiveness and feasibility of these approaches.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of opioid misuse among patients with chronic pain by enhancing their social support and mental health.

How similar studies have gone: Previous research has shown that cognitive behavioral therapy and social support interventions can effectively reduce loneliness in other populations, suggesting potential for success in this novel application.

Where this research is happening

  • University of Washington
    Seattle, United States
    Active

Researchers

  • Principal investigator: Tong, Sebastian — University of Washington
  • Study coordinator: Tong, Sebastian

Related research

Other NIH-funded projects on the same topics.

  • Primary care loneliness programs to prevent suicide

    This project will try two short loneliness programs—social prescribing and brief cognitive therapy—in primary care to help adults who feel lonely and may have suicidal thoughts.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11084462

  • HEARTS hypertension and diabetes care in Guatemala

    This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11645315

  • Primary Care HEART-NET: boosting access to research in the Deep South

    A collaboration across three universities will build primary care research networks in Alabama, Arkansas, and Mississippi to improve access to care and help prevent and manage chronic diseases.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11618658

  • Primary Care Bridge: Building Research in Diverse Geographic Settings

    A national network hub in New Mexico will connect rural clinics and communities to faster, more usable primary care research so patients in underserved areas can benefit from new evidence.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11618652

  • WREN: Expanding Research Capacity in Rural Primary Care Clinics

    A nationwide network in Wisconsin will strengthen rural primary care clinics to participate in real-world research and bring more clinical trials to communities.

    NIH research University of Wisconsin-Madison · Madison, United States · NIH-11618649

  • Primary care research network in Oklahoma to boost rural patient trials

    A nationwide NIH-supported effort to strengthen Oklahoma’s primary care research network so doctors can run big clinical trials and real‑world studies in rural communities.

    NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11618645

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.