Helping pregnant people decide about prenatal genetic testing to improve pregnancy outcomes

Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes

NIH-funded research Cleveland Clinic Lerner Com-Cwru · NIH-11295474

This project will build a friendly digital tool to help pregnant people understand prenatal genetic screening and diagnostic options and make choices that match their values.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCleveland Clinic Lerner Com-Cwru NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11295474 on NIH RePORTER

What this research studies

As a pregnant person, you'll hear about a new digital tool being designed to explain prenatal genetic screening and diagnostic tests in plain language. The team will create the tool with input from patients and clinicians, use usability testing and interviews to refine it, and pilot it in obstetric clinics to see how it affects understanding and choices. The work may use AI to tailor information to individual needs and track whether patients get timely access to recommended follow-up testing. Results are intended to improve how genomic information is shared and used during prenatal care.

Who could benefit from this research

Good fit: Pregnant people who are considering or offered prenatal genetic screening or diagnostic testing and want decision support are ideal candidates.

Not a fit: People who are not pregnant or who are not considering prenatal genetic testing are unlikely to directly benefit from this project.

Why it matters

Potential benefit: If successful, this could help pregnant people make clearer, values-based decisions about prenatal genetic testing and improve pregnancy and newborn outcomes.

How similar studies have performed: Previous decision aids for prenatal testing have improved understanding and satisfaction, but a digital, AI-enhanced decision tool is a newer approach with limited prior testing.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.