NIH-funded research R01 grant

Helping pregnant and postpartum people reduce tobacco and cannabis use

Official title: Partnering with Pregnant and Postpartum Women to Co-Create a Novel Intervention to Reduce Tobacco and Cannabis Use

Funded at University of Pittsburgh at Pittsburgh · NIH-11192777 · Data updated 2026-11-12

This project partners with pregnant and postpartum people who use tobacco and cannabis to co-create a program that treats depression to help them quit or cut down on smoking.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 15, 2024
Project endAugust 31, 2027
Funding year2025
Award (this year)$573,157
NIH project number5R01DA057946-02
Project IDNIH-11192777 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pregnant or recently postpartum people who currently or recently used both tobacco and cannabis and experienced depressive symptoms during pregnancy.

Less likely to help

People who are not pregnant or postpartum, who only use one substance, or who did not have prenatal depressive symptoms may not benefit from this specific intervention.

What this research studies

You would work with researchers and a community collaborative to share your experiences with tobacco and cannabis use during and after pregnancy. The team will co-create an interview guide and conduct in-depth interviews with about 35 pregnant or parenting people who used both substances and experienced prenatal depressive symptoms. Researchers and community members will code and analyze themes from those interviews and then use an intervention mapping process to design a support program targeting depressive symptoms to help reduce tobacco and cannabis use. The final intervention will be built with direct input from people with lived experience so it better fits real needs and contexts.

Why it matters

Potential benefit: If successful, this could create a patient-designed program that helps pregnant and postpartum people stop using tobacco and cannabis and improves health for parents and infants.

How similar studies have gone: Treating depressive symptoms has supported smoking cessation in prior research, but co-created programs that target both tobacco and cannabis use during pregnancy are relatively new.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: De Genna, Natacha — University of Pittsburgh at Pittsburgh
  • Study coordinator: De Genna, Natacha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.