Helping people with HIV or TB in South Africa quit smoking and stay in care
Treatment Development for Smoking Cessation and Engagement in HIV/TB Care in South Africa
A tailored program to help adults with HIV or tuberculosis in South Africa stop smoking and keep up with their HIV/TB treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11086126 on NIH RePORTER |
What this research studies
This project will adapt and combine cognitive-behavioral smoking-cessation support with strategies to improve HIV and TB treatment adherence for people in South Africa. Participants will be offered counseling and follow-up designed for the local clinic setting, drawing on successful approaches used in prior US and South African trials. The team will test whether the tailored program is acceptable, feasible, and can increase quit rates and treatment engagement. Findings will guide a larger trial if the approach looks promising.
Who could benefit from this research
Good fit: Adults (21+) in South Africa who currently smoke and are living with HIV and/or have a new TB diagnosis are the ideal candidates.
Not a fit: People who do not smoke, who are not living with HIV or TB, or who cannot attend local clinic sessions are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, this program could help more people quit smoking, improve HIV and TB treatment adherence, and reduce treatment failure and death.
How similar studies have performed: Earlier cognitive-behavioral programs showed increased quitting among people with HIV in a US trial and improved ART adherence in Cape Town, but combining and tailoring these approaches for HIV/TB care in South Africa is relatively new.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: O'cleirigh, Conall Michael — Massachusetts General Hospital
- Study coordinator: O'cleirigh, Conall Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.