Helping people who inject drugs reduce their risk of HIV using a new support approach.

Promoting HIV risk reduction among people who inject drugs: A stepped care approach using contingency management with PrEP navigation

NIH-funded research Yale University · NIH-11097140

This study is looking to help people who inject drugs stay safe from HIV by trying out a new program that offers rewards for making healthy choices, while also connecting them to important services like clean syringes and medication support.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11097140 on NIH RePORTER

What this research studies

This research focuses on improving HIV prevention for people who inject drugs (PWID) by using a stepped care approach that combines contingency management with navigation for pre-exposure prophylaxis (PrEP). The study aims to engage PWID in community-based settings where they can access essential services like syringe programs and medications for opioid use disorder. Participants will be randomly assigned to receive either a new intervention that includes rewards for behavior change or standard treatment. The goal is to evaluate how effective this new approach is in increasing access to and adherence to HIV prevention methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who inject drugs and are eligible for PrEP.

Not a fit: Patients who do not inject drugs or are not at risk for HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance HIV prevention efforts among people who inject drugs, potentially reducing new infections.

How similar studies have performed: Previous research has shown that contingency management can be effective in promoting behavior change in substance use and health interventions, suggesting potential success for this approach.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.