Helping people understand and receive important genetic health information
RESPECT3: A Randomized type 1 hybrid Effectiveness-implementation Study of returning actionable genetic PanEl researCh resulTs
['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11093993
This project helps us learn the best ways to share important genetic health information with people who have participated in large health studies.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11093993 on ClinicalTrials.gov |
What this research studies
Many large health studies collect DNA samples to understand how genes, lifestyle, and environment affect health. Sometimes, these DNA tests reveal genetic changes that could significantly impact a person's future health or their family's health. This project builds on previous work to find the best ways to educate participants about these findings and offer them their results. We are using an online education tool, including a chatbot, to help 1250 Penn Biobank participants understand the benefits and limitations of receiving their genetic results and how those results will be shared.
Who could benefit from this research
Good fit: This project is specifically for participants of the Penn Biobank who may have actionable genetic results or serve as controls.
Not a fit: Patients not enrolled in the Penn Biobank or those whose genetic results are not part of this specific research will not directly benefit from this project.
Why it matters
Potential benefit: If successful, this work could help ensure that people receive important genetic health information in a clear and helpful way, empowering them to make informed decisions about their health.
How similar studies have performed: Previous RESPECT studies have shown that using online education and consent tools is feasible and leads to positive experiences for patients receiving genetic information.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRADBURY, ANGELA R. — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: BRADBURY, ANGELA R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.