Helping people quit smoking for good

A clinical trial of adaptive treatment for early smoking cessation relapse

NIH-funded research Medical University of South Carolina · NIH-11121737

This project helps daily smokers find the best way to quit cigarettes, especially if their first attempt isn't successful.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11121737 on NIH RePORTER

What this research studies

Many people try to quit smoking, but it can be tough, and often the first attempt doesn't stick. This project looks at different ways to help you quit if your first try with medication doesn't work out. We want to see if switching to a different medication or even trying e-cigarettes could be more helpful than trying the same thing again. The goal is to find a personalized approach that gives you the best chance to stop smoking for good.

Who could benefit from this research

Good fit: Ideal candidates are daily smokers aged 21 or older in South Carolina and Alabama who are ready to set a quit date.

Not a fit: Patients who are not daily smokers or are not located in South Carolina or Alabama would not be eligible for this particular project.

Why it matters

Potential benefit: If successful, this project could provide clearer guidance on how to adjust smoking cessation treatments when initial attempts are unsuccessful, leading to higher success rates for patients.

How similar studies have performed: This project explores a novel adaptive treatment approach for smoking cessation, as few previous trials have specifically investigated the best path forward after initial treatment failure.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Centers for Disease ControlCenters for Disease Control and PreventionCenters for Disease Control and Prevention (U.S.)
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.