NIH-funded research R01 grant

Helping people in substance use treatment reduce tobacco harm

Official title: Evaluating a tobacco harm reduction strategy among clients enrolled in substance use disorder treatment

Funded at Medical University of South Carolina · NIH-11192931 · Data updated 2026-11-12

This study is looking at ways to help people who are getting treatment for substance use disorders quit smoking by encouraging them to switch from regular cigarettes to safer options like e-cigarettes, making it easier for them to improve their health while tackling both issues at the same time.

More Substance Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startSeptember 15, 2024
Project endMay 31, 2029
Funding year2025
Award (this year)$625,247
NIH project number5R01DA059969-02
Project IDNIH-11192931 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals currently enrolled in substance use disorder treatment who also smoke cigarettes.

Less likely to help

Patients who do not smoke or are not enrolled in substance use disorder treatment may not receive any benefit from this research.

What this research studies

This research investigates how to effectively reduce tobacco use among individuals undergoing treatment for substance use disorders. It focuses on implementing low-intensity harm reduction strategies that encourage smokers to switch from combustible cigarettes to less harmful alternatives, such as e-cigarettes. The approach aims to improve health outcomes for patients by addressing both their substance use and smoking habits simultaneously. By evaluating the effectiveness of these strategies, the research seeks to enhance the overall treatment experience for patients.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for patients by reducing tobacco-related illnesses among those in substance use disorder treatment.

How similar studies have gone: Previous research has shown that harm reduction strategies can be effective in improving health outcomes for smokers, particularly in populations with high rates of substance use.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Mcclure, Erin a — Medical University of South Carolina
  • Study coordinator: Mcclure, Erin a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.