Helping people cope with stress and trauma

Treatment of Stress-Related Psychopathology: Targeting Maladaptive and Adaptive Event Processing

NIH-funded research Case Western Reserve University · NIH-11180429

This project looks for better ways to help people overcome the lasting effects of stressful or traumatic experiences, especially for conditions like PTSD and depression.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11180429 on NIH RePORTER

What this research studies

Many people find relief from current therapies for PTSD and depression, but some still struggle with symptoms or drop out of treatment. This project aims to create more effective and precise therapies by focusing on common ways people process stressful events. We want to understand both unhelpful patterns and helpful coping skills. By addressing these core processes, we hope to develop new approaches that lead to more lasting recovery and prevent symptoms from returning.

Who could benefit from this research

Good fit: Individuals experiencing symptoms of posttraumatic stress disorder (PTSD) or depression, especially those who have experienced stressful or traumatic life events, would be ideal candidates.

Not a fit: Patients whose mental health challenges are unrelated to stress or trauma processing may not directly benefit from this specific approach.

Why it matters

Potential benefit: If successful, this work could lead to new, more effective, and longer-lasting therapies for individuals struggling with PTSD and depression, reducing symptoms and preventing relapse.

How similar studies have performed: This project builds upon decades of experimental and clinical studies that have identified key processes involved in how people cope with stressful events.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.