NIH-funded research NIH-funded research

Helping patients with intermediate-risk thyroid cancer make decisions about radioactive iodine treatment

Official title: Use of a decision aid to resolve uncertainty about radioactive iodine treatment in patients with intermediate-risk thyroid cancer: the Radiance trial

Funded at Georgetown University · NIH-11225699 · Data updated 2026-11-12

This study is here to help people with intermediate-risk thyroid cancer understand the pros and cons of using radioactive iodine treatment after surgery, so they can make informed choices about their care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGeorgetown University
NIH-funded
Lab location1 site (Washington, United States)
Project startSeptember 5, 2022
Project endJanuary 31, 2030
Funding year2025
Award (this year)$767,922
NIH project number4UH3DE031248-03
Project IDNIH-11225699 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with intermediate-risk differentiated thyroid cancer who are considering treatment options.

Less likely to help

Patients with low-risk or high-risk differentiated thyroid cancer may not benefit from this research.

What this research studies

This research aims to assist patients diagnosed with intermediate-risk differentiated thyroid cancer in understanding the risks and benefits of radioactive iodine (RAI) treatment. It addresses the uncertainty many patients face when deciding between surgery alone or surgery combined with RAI, which can have significant side effects. The study will utilize a decision aid to provide clear information about potential outcomes, side effects, and quality of life impacts associated with RAI. By focusing on patient-centered decision-making, the research seeks to empower individuals to make informed choices regarding their treatment options.

Why it matters

Potential benefit: If successful, this research could lead to better-informed treatment decisions and improved quality of life for patients with intermediate-risk thyroid cancer.

How similar studies have gone: Previous research has shown that decision aids can effectively improve patient understanding and satisfaction in treatment choices, indicating a promising approach in this context.

Where this research is happening

  • Georgetown University
    Washington, United States
    Active

Researchers

  • Principal investigator: Jonklaas, Jacqueline — Georgetown University
  • Study coordinator: Jonklaas, Jacqueline

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.