Helping patients start alcohol treatment after a hospital stay with counseling, medicines, and online CBT
Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications, and CBT4CBT: A randomized clinical trial in a diverse patient population
This trial compares three ways to help hospitalized adults with untreated alcohol use disorder start treatment and cut down on drinking: a brief counseling visit, counseling plus medication, or both plus computer-delivered CBT.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11116991 on NIH RePORTER |
What this research studies
You would be randomly assigned to one of three approaches while hospitalized: a short negotiated interview with a referral and a two-week phone booster; that same brief intervention plus medications for alcohol use disorder; or the brief intervention, medications, and access to CBT4CBT, an online cognitive behavioral program. The team plans to enroll about 450 patients from diverse racial and ethnic backgrounds and follow you after discharge to see who connects with treatment and how much you drink. They will also collect information about social needs like housing instability and medical mistrust to understand how these factors affect treatment engagement. Participation involves an in-hospital interaction and phone or online follow-up after you leave the hospital.
Who could benefit from this research
Good fit: Ideal participants are adults hospitalized with untreated alcohol use disorder who are medically stable for discharge and not already engaged in AUD treatment.
Not a fit: People without alcohol use disorder, those already in AUD treatment, those who are medically unstable, or those unable to use phone/online tools are unlikely to benefit from this trial.
Why it matters
Potential benefit: If successful, this approach could help more people leave the hospital already connected to effective alcohol treatment and reduce harmful drinking after discharge.
How similar studies have performed: Brief hospital-based interventions and medications for AUD have shown benefit in prior studies and digital CBT has promising early results, but combining all three approaches in hospitalized, diverse patients is relatively new.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Edelman, E. Jennifer — Yale University
- Study coordinator: Edelman, E. Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.