Helping patients come off breathing machines

ACT_NOW Weaning

NIH-funded research Duke University · NIH-11471735

This project aims to find better ways to help patients safely stop using breathing machines in the hospital.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11471735 on NIH RePORTER

What this research studies

When patients are very sick, they often need a breathing machine to help them recover. This project focuses on improving the process of gradually reducing support from these machines until patients can breathe on their own. We want to make this transition smoother and faster, helping patients regain their independence and leave the hospital sooner. The goal is to develop and test new strategies that make weaning more successful and less stressful for patients.

Who could benefit from this research

Good fit: Patients who are currently on a breathing machine in an intensive care unit and are beginning the process of being weaned off.

Not a fit: Patients who are not on a breathing machine or whose condition does not allow for weaning may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could help patients spend less time on breathing machines, recover more quickly, and reduce complications associated with prolonged ventilation.

How similar studies have performed: While weaning protocols are common, this project likely explores novel or optimized approaches building on existing knowledge to improve outcomes.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.