NIH-funded research R21 grant

Helping patients and families make informed decisions about dementia therapies

Official title: Helping Patients, Families, and Clinicians Make Shared Decisions about Therapies for Dementia

Funded at University of Colorado Denver · NIH-10949237 · Data updated 2026-11-12

This study is creating a helpful guide for patients, families, and doctors to make better choices about dementia treatments, especially a new drug called Lecanemab-IRMB, by understanding what people need to know about the benefits and risks of these options.

More Dementia research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 15, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$234,000
NIH project number1R21AG088955-01
Project IDNIH-10949237 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include patients diagnosed with Alzheimer's disease and their caregivers who are considering treatment options.

Less likely to help

Patients who are not diagnosed with Alzheimer's disease or those who are not considering any dementia therapies may not benefit from this research.

What this research studies

This research focuses on developing a patient decision aid to assist patients, families, and clinicians in making informed choices about dementia therapies, particularly the newly approved drug Lecanemab-IRMB. The project will involve a needs assessment to understand the challenges faced in discussing treatment options and will utilize a user-centered approach to create effective communication tools. By facilitating shared decision-making, the research aims to ensure that patients and families are fully aware of the potential benefits and risks associated with dementia treatments.

Why it matters

Potential benefit: If successful, this research could empower patients and families to make better-informed decisions regarding dementia therapies, leading to improved satisfaction and outcomes.

How similar studies have gone: Previous research has shown that decision aids can significantly improve patient understanding and satisfaction in treatment decision-making, indicating a promising approach.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Matlock, Daniel D — University of Colorado Denver
  • Study coordinator: Matlock, Daniel D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.