Helping older women with gynecologic cancer recover their strength and function
Official title: Promoting gynecologic cancer patients with frailty to achieve functional recovery cohort study (PROOF Cohort Study)
Funded at University of California, San Francisco · NIH-10975759 · Data updated 2026-11-12
This study is looking at older women with advanced gynecologic cancers, like ovarian and uterine cancer, to understand how their health and strength change over time, so we can find better ways to help them recover and improve their quality of life.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $349,561 |
| NIH project number | 1R03AG088902-01 |
| Project ID | NIH-10975759 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older women, particularly those aged 62 and above, who have been diagnosed with advanced ovarian or uterine cancer.
✕Less likely to help
Patients with early-stage gynecologic cancers or those who are not experiencing significant functional decline may not benefit from this research.
What this research studies
This research focuses on older women diagnosed with advanced gynecologic cancers, such as ovarian and uterine cancer, who often experience significant physical decline due to their illness. The study aims to objectively assess frailty in these patients to better understand their functional recovery needs. By evaluating factors like malnutrition and muscle wasting, the research seeks to improve treatment decisions and enhance quality of life. Patients will be monitored over time to determine how frailty impacts their recovery and treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance recovery and quality of life for older women with gynecologic cancers.
How similar studies have gone: Previous research has shown that assessing frailty can lead to better treatment outcomes in older cancer patients, indicating a promising approach in this area.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Cham, Stephanie — University of California, San Francisco
- Study coordinator: Cham, Stephanie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.