Helping muscles heal from scarring using special cells
Engineering Mesenchymal Stromal Cells to treat Muscle Fibrosis
['FUNDING_OTHER'] · COLORADO STATE UNIVERSITY · NIH-11092212
This research explores how specially prepared cells might help reduce muscle scarring, which is a problem in conditions like muscular dystrophy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLORADO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (FORT COLLINS, UNITED STATES) |
| Trial ID | NIH-11092212 on ClinicalTrials.gov |
What this research studies
Our muscles can sometimes develop scarring, called fibrosis, which makes them stiff and weak. This project looks at using special cells called mesenchymal stromal cells (MSCs), which are known for their ability to help repair tissues. We are developing a new way to coat these MSCs with a special gel that helps them become more effective at breaking down scar tissue. By understanding how these coated cells work, we hope to find a new way to reduce muscle fibrosis and improve muscle health.
Who could benefit from this research
Good fit: This early-stage research is not yet recruiting patients, but future studies might involve individuals experiencing muscle fibrosis due to conditions such as muscular dystrophy.
Not a fit: Patients without muscle fibrosis or those with conditions not involving this type of scarring may not directly benefit from this specific approach.
Why it matters
Potential benefit: If successful, this approach could lead to new treatments that reduce muscle scarring and improve muscle function for people with conditions like muscular dystrophy.
How similar studies have performed: While MSCs have been explored in many clinical trials, this specific method of engineering MSCs with gel coatings to enhance their scar-reducing abilities is a novel approach.
Where this research is happening
FORT COLLINS, UNITED STATES
- COLORADO STATE UNIVERSITY — FORT COLLINS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WONG, SING-WAN — COLORADO STATE UNIVERSITY
- Study coordinator: WONG, SING-WAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.