Helping men start and stay on daily PrEP

Intervention to Enhance Prep Persistence Among Men

NIH-funded research Brown University · NIH-11367302

A short patient navigation program aims to help men start and stay on daily PrEP so they can lower their chance of getting HIV.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrown University NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-11367302 on NIH RePORTER

What this research studies

You would be invited to a randomized trial testing a brief, strengths-based patient navigation program called RAMP-IT-UP at community health centers. Navigators work with you to overcome social and practical barriers to starting PrEP, picking up refills, and keeping clinic appointments. The trial compares this navigation approach to usual care and measures pharmacy fills, PrEP blood levels, and clinic retention over time. The study also looks at the program's costs to see if it is affordable for clinics to offer.

Who could benefit from this research

Good fit: Men who are eligible for daily PrEP and receiving care at participating community health centers, especially those facing barriers to starting or staying on medication, are the ideal candidates.

Not a fit: People who are HIV-positive, not eligible for or not interested in PrEP, or who are not men are unlikely to benefit from this trial.

Why it matters

Potential benefit: If successful, the program could help more men start and continue PrEP, lowering their risk of HIV infection.

How similar studies have performed: A prior pilot of RAMP-IT-UP showed improved PrEP starts, pharmacy fills, blood levels, and 3- and 6-month retention, so this trial builds on promising early results.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.