Helping Lung Transplants Last Longer
Pathways Regulating Lung Transplant Tolerance
['FUNDING_P01'] · WASHINGTON UNIVERSITY · NIH-11112098
This research looks for new ways to help the body accept a transplanted lung and prevent rejection, aiming for better long-term success for patients.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11112098 on ClinicalTrials.gov |
What this research studies
Lung transplants are a life-saving option, but many patients face challenges with their new lungs lasting a long time. This research believes that current anti-rejection medicines might not be perfectly suited for the unique needs of lung transplants. We are working to uncover the specific ways the body's immune system interacts with a transplanted lung. By understanding these interactions, we hope to find new targets for medicines that can prevent rejection and help the body accept the new lung more effectively. This work uses advanced models to study these processes, with the ultimate goal of improving outcomes for people who receive lung transplants.
Who could benefit from this research
Good fit: This research is ultimately for patients who have received or will receive a lung transplant.
Not a fit: Patients not undergoing or considering lung transplantation would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new, more effective treatments that help transplanted lungs last longer and improve the quality of life for patients.
How similar studies have performed: This research builds on existing knowledge about lung transplantation and aims to discover novel pathways for preventing rejection.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KREISEL, DANIEL — WASHINGTON UNIVERSITY
- Study coordinator: KREISEL, DANIEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.