Helping Latin American adults with HIV stay engaged in care

A Randomized Controlled Trial of an Intervention to Improve Engagement in HIV Care

NIH-funded research Massachusetts General Hospital · NIH-11132993

This project offers a five-session, health worker–delivered video program to help Latin American adults with HIV who have detectable virus stay in care and stick with treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11132993 on NIH RePORTER

What this research studies

You would be randomly assigned to either ADELANTE — a five-session, health worker–delivered video intervention that helps you problem-solve barriers to care, build confidence, and connect to resources — or an enhanced care condition that provides five reminder phone calls. The trial plans to enroll 250 Latin American adults with HIV who have had detectable virus (HIV RNA ≥200 copies/mL) at least six months after their index visit. It will be run at two Ryan White–supported clinics in U.S. Ending the HIV Epidemic (EHE)–identified areas and will use existing clinic staff and community partners to deliver the program. The main outcomes are viral suppression at 12 months and whether the program reduces emergency department visits and hospitalizations.

Who could benefit from this research

Good fit: Latin American adults (age ≥18) living with HIV in the U.S. who have viral non-suppression (HIV RNA ≥200 copies/mL) and receive care at one of the participating Ryan White–supported clinics.

Not a fit: People who are already virally suppressed, are under 18, or cannot access the participating clinics are unlikely to benefit from this specific program.

Why it matters

Potential benefit: If successful, the program could help more Latin American patients stay on treatment, reach viral suppression, and reduce emergency visits and hospital stays.

How similar studies have performed: Similar strategies showed promise in earlier pilot work, but this larger randomized trial is designed to confirm effectiveness in real clinic settings.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.