Helping ICU survivors regain everyday skills through cognitive rehabilitation

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III Pilot Randomized Clinical Trial (RETURN-III Pilot RCT)

NIH-funded research Veterans Health Administration · NIH-11191423

This study is testing a new computer program to help people who have survived a serious illness and are having trouble with thinking and memory, so they can better manage everyday tasks like taking medications and handling money, ultimately helping them live more independently and enjoy a better quality of life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11191423 on NIH RePORTER

What this research studies

This research focuses on improving the cognitive abilities of patients who have survived critical illness and are experiencing long-term cognitive impairments, often resembling dementia. The study utilizes a novel Computerized Cognitive Rehabilitation (CCR) approach, which has been adapted from previous successful interventions. Participants will engage in a structured program designed to enhance their ability to manage daily tasks, such as handling medications and finances, thereby promoting independence and improving quality of life. The trial aims to assess the effectiveness of this intervention in a randomized controlled setting.

Who could benefit from this research

Good fit: Ideal candidates for this research are ICU survivors who are experiencing long-term cognitive impairments following their critical illness.

Not a fit: Patients who have not experienced cognitive impairments or those who are not ICU survivors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the cognitive functioning and daily living skills of ICU survivors, leading to improved independence and quality of life.

How similar studies have performed: Previous studies have shown success with cognitive rehabilitation approaches for similar patient populations, indicating a promising avenue for this research.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.