Helping homeless youth prevent opioid use through housing and support services

Prevention of OUD: The HOME (Housing, Opportunities, Motivation and Engagement) Randomized Trial

NIH-funded research Ohio State University · NIH-10168176

This study is looking at how giving stable homes and support services can help homeless and street-involved young people avoid using opioids, by focusing on getting them safe housing first before tackling their substance use.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-10168176 on NIH RePORTER

What this research studies

This research investigates how providing stable housing and support services can help prevent opioid use among homeless and street-involved youth. It employs a randomized controlled trial design to assess the effectiveness of a 'Housing First' approach, which prioritizes securing stable living conditions before addressing substance use issues. By focusing on this vulnerable population, the study aims to understand the relationship between housing stability and the reduction of opioid use and related risk behaviors. Participants will receive comprehensive support, including access to mental health services and substance use interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are homeless or street-involved youth aged 21 and older who are at risk for opioid use.

Not a fit: Patients who are not homeless or do not have substance use issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce opioid use and improve overall health outcomes for homeless youth.

How similar studies have performed: Previous research has shown that housing-first interventions can effectively reduce substance use and improve health outcomes, suggesting a promising approach for this population.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Centers for Disease Control and Prevention (U.S.)
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.