Helping families break cycles of stress and improve parenting across generations

Intervention Impacts on Child Wellbeing and Parenting across Generations

NIH-funded research Duke University · NIH-11181155

Looks at whether helping parents now leads to better parenting by their children later and healthier outcomes for grandchildren.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11181155 on NIH RePORTER

What this research studies

This project follows people who grew up in families with high stress, violence, food insecurity, or parental substance and mental health problems and now are parenting their own children. Researchers compare those who received supports (like an income supplement) or parenting-focused interventions to see how those early supports affect parenting and child health across three generations. The team uses long-term data from the Great Smoky Mountains Study, including participants from 11 North Carolina counties and members of the Eastern Band of Cherokee. They measure family warmth, aggression, stability, food security, and mental health in parents and their children over time.

Who could benefit from this research

Good fit: Ideal candidates are parents or caregivers who have experienced family stress, instability, food insecurity, or aggression, particularly people from the original Great Smoky Mountains Study cohorts or their children.

Not a fit: People without parenting responsibilities or those who do not live in or descend from the study communities are unlikely to gain direct benefit from participating.

Why it matters

Potential benefit: If successful, this work could show that targeted supports for parents reduce family stress and improve parenting and child health across generations.

How similar studies have performed: Previous studies show income supplements and parenting programs can improve child behavior and wellbeing, but strong evidence about lasting effects across multiple generations is limited.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.