Helping families and schools in Gauteng make informed choices to prevent HPV and other infection-related cancers

Multi-level shared decision-making intervention to prevent cancer in South Africa

NIH-funded research Brigham and Women's Hospital · NIH-11373136

This project offers school and family programs to help parents, teachers, and adolescents in Gauteng, South Africa make informed choices that prevent cervical and other infection-related cancers.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11373136 on NIH RePORTER

What this research studies

If you are a parent, teacher, or adolescent in Gauteng, this project works with schools and the Department of Health to improve how cancer prevention information and services are delivered. It focuses on clearer education, better communication tools for teachers and caregivers, and trusted channels for shared decision-making about prevention like HPV vaccination. The team will refine materials and delivery methods to reach girls, boys, and young people outside the public school system and address past drops in program completion. The goal is to make it easier for families to understand options and follow through with prevention steps.

Who could benefit from this research

Good fit: Ideal candidates are adolescents (girls and boys), their parents or caregivers, and school staff in Gauteng Province, South Africa, especially those eligible for HPV vaccination or who are out of school.

Not a fit: People who live outside the project area or adults who have already completed recommended cancer-prevention measures may not directly benefit from this program.

Why it matters

Potential benefit: If successful, the approach could increase uptake of cancer-preventing measures such as HPV vaccination and reduce infection-related cancer risk among adolescents in high-burden communities.

How similar studies have performed: School-based HPV and infection-related cancer prevention programs have shown promise in some settings and initial national rollout in South Africa was promising but later coverage dropped, so this project builds on prior work to address gaps.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAnogenital cancerCancer BurdenCancer Cause
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.