Helping East African children and young adults with type 1 diabetes keep blood sugar in a healthy range
Diabetes in African Youth: Improving Glucose Time-In-Range
This project gives flash continuous glucose monitors to young people with type 1 diabetes in East Africa to help them spend more time with blood sugar in a healthy range compared with regular fingerstick checks.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11386561 on NIH RePORTER |
What this research studies
You would join a randomized trial for people aged 4–26 years with type 1 diabetes in East Africa. All participants get monthly diabetes education and are followed for outcomes; half receive unblinded flash continuous glucose monitors so they can view real-time glucose, while the other half do fingerstick checking at least three times daily and wear a blinded CGM for outcome measurement. The study includes about 180 participants (90 per group) and measures the percent time blood glucose is between 70–180 mg/dL and time spent in hypoglycemia. The researchers will also look at whether providing CGM is cost effective in a low-resource setting.
Who could benefit from this research
Good fit: Ideal candidates are children and young adults aged 4–26 years with type 1 diabetes who live in the East African study area and can attend monthly visits.
Not a fit: People without type 1 diabetes, those outside the 4–26 age range, or individuals who are not located in the East African study region would not be eligible and likely would not benefit directly from participating.
Why it matters
Potential benefit: If successful, this approach could increase the amount of time young people spend with blood sugar in a safe range and reduce dangerous highs and lows, potentially improving short- and long-term health in low-resource settings.
How similar studies have performed: Continuous glucose monitoring has improved time-in-range in many studies from high-income countries, but randomized data and cost-effectiveness information are limited for low-resource East African settings.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Moran, Antoinette M. — University of Minnesota
- Study coordinator: Moran, Antoinette M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.