Helping critically ill children with personalized care
Collaborative Pediatric Critical Care Research Network - Clinical Site
This effort helps children aged 0-11 who are critically ill with sepsis and organ failure by exploring personalized treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State Higher Education System--University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11170723 on NIH RePORTER |
What this research studies
Children's Hospital of Philadelphia is a key site in a network dedicated to improving care for critically ill children. This specific project focuses on a large clinical trial for children aged 0-11 who develop multiple organ problems due to sepsis. Researchers are looking at personalized ways to manage their immune response, potentially using anti-inflammatory medications like Actemra. The goal is to find targeted treatments that can better support these very sick young patients.
Who could benefit from this research
Good fit: Ideal candidates are critically ill children aged 0-11 years old who are experiencing multiple organ dysfunction syndrome caused by sepsis.
Not a fit: Patients outside the 0-11 age range or those with critical illnesses not related to sepsis-induced multiple organ dysfunction syndrome would not directly benefit from this specific trial.
Why it matters
Potential benefit: If successful, this work could lead to more effective, personalized treatments for children with severe sepsis and organ failure, improving their chances of recovery.
How similar studies have performed: The Collaborative Pediatric Critical Care Research Network has a history of advancing pediatric critical care, and this project builds on that foundation with a large randomized controlled trial.
Where this research is happening
Salt Lake City, United States
- Utah State Higher Education System--University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Zuppa, Athena F. — Utah State Higher Education System--University of Utah
- Study coordinator: Zuppa, Athena F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.