Helping create and run clinical trials for childhood cancers
Development, review, and conduct of Children's Oncology Group (COG) Clinical Trials
This work supports experts who design and run clinical trials to find better treatments and care for children and teens with cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Research Institute NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11162479 on NIH RePORTER |
What this research studies
From a patient’s perspective, this effort coordinates doctors and hospitals across the Children’s Oncology Group to write safe protocols and enroll children in trials. It helps central committees (like the Renal Tumor Committee) develop trials, oversees how trials are carried out at more than 200 member sites, and supports studies of frontline treatments, relapsed disease, biology, and survivorship. The role helps make sure trials follow rules, collect useful biological samples, and share results so more kids can benefit. Many thousands of children have been enrolled in COG efforts, and this work keeps that system running and improving.
Who could benefit from this research
Good fit: Children and adolescents diagnosed with childhood cancers who receive care at a Children’s Oncology Group member hospital, including those with newly diagnosed or recurrent disease, are the typical candidates for trials supported by this work.
Not a fit: Patients not treated at COG member centers, those whose cancer type has no open trial, and healthy children would not directly benefit from this grant.
Why it matters
Potential benefit: If successful, this work could speed development of safer, more effective treatments and improve quality of life and long-term outcomes for children with cancer.
How similar studies have performed: The Children’s Oncology Group has a long history of successful trials that improved survival and supportive care for many childhood cancers, and this work continues that established effort.
Where this research is happening
Washington, United States
- Children's Research Institute — Washington, United States (Active)
Researchers
- Principal investigator: Dome, Jeffrey S — Children's Research Institute
- Study coordinator: Dome, Jeffrey S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.