Helping Children with Undiagnosed Conditions in Southern California
Southern California Undiagnosed Disease Network
This program helps children and youth in Southern California who have rare, undiagnosed health conditions find answers and receive proper care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11145766 on NIH RePORTER |
What this research studies
This program aims to shorten the difficult journey for patients with rare, undiagnosed diseases by offering comprehensive evaluations. It brings together experts from UC Irvine, Children’s Hospital of Orange County, and Ambry Genetics to provide advanced genetic testing and clinical insights. This partnership also reaches out to underserved communities, ensuring more families can access specialized care. The goal is to move beyond wrong diagnoses and missed treatment opportunities, providing clarity and a path forward for these children.
Who could benefit from this research
Good fit: Children and youth (0-21 years old) in Southern California who have a suspected rare disease that has not yet been diagnosed would be ideal candidates.
Not a fit: Patients whose conditions have already been diagnosed or who are outside the specified age range or geographic area may not directly benefit from this specific program.
Why it matters
Potential benefit: If successful, this program could provide accurate diagnoses and appropriate care much faster for children with mysterious health conditions, improving their quality of life.
How similar studies have performed: This program is part of a national Undiagnosed Disease Network (UDN), indicating that similar approaches have been established and found valuable across the country.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Vilain, Eric J. — University of California-Irvine
- Study coordinator: Vilain, Eric J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.