Helping children with severe infections in critical care
Collaborative Pediatric Critical Care Research Network - Clinical Site
This effort aims to understand and improve how children fight severe infections, called sepsis, in the hospital.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State Higher Education System--University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11170738 on NIH RePORTER |
What this research studies
When children get very sick from an infection, it can lead to a life-threatening condition called sepsis, where their organs may start to fail. This work is part of a larger network focused on finding better ways to care for critically ill children. Researchers plan to conduct a trial to see if personalized treatments can help children with sepsis by improving their ability to fight infection and control inflammation. They will collect blood samples from children with sepsis to learn more about their immune responses.
Who could benefit from this research
Good fit: Children aged 0-11 years old who are hospitalized with severe infections leading to sepsis and multiple organ dysfunction may be candidates.
Not a fit: Patients who do not have sepsis or are outside the specified age range would not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to new, personalized treatments that save the lives of children suffering from severe sepsis and organ failure.
How similar studies have performed: This approach explores new technologies for personalized immunomodulation, representing a novel strategy for a condition where past treatments have had limited success.
Where this research is happening
Salt Lake City, United States
- Utah State Higher Education System--University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Carcillo, Joseph a — Utah State Higher Education System--University of Utah
- Study coordinator: Carcillo, Joseph a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.