NIH-funded research U01 cooperative agreement

Helping Cambodian people living with HIV quit smoking using tailored smartphone messages and support

Official title: Ending Tobacco Use through Interactive Tailored Messaging for Cambodian People Living with HIV/AIDS (EndIT)

Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11163553 · Data updated 2026-11-12

A program offers personalized smartphone messages plus medication and counseling to help Cambodian adults living with HIV stop smoking.

More AIDS research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionH. Lee Moffitt Cancer Ctr & Res Inst
NIH-funded
Lab location1 site (Tampa, United States)
Project startSeptember 17, 2021
Project endAugust 31, 2027
Funding year2025
Award (this year)$467,359
NIH project number5U01CA261598-05
Project IDNIH-11163553 on NIH RePORTER

Who could benefit from this research

Could help

Cambodian adults living with HIV who currently smoke cigarettes, are receiving HIV care (ART), and have access to a smartphone are ideal candidates.

Less likely to help

People who do not smoke, are not living with HIV, lack access to a smartphone, or do not want to use mobile-based support are unlikely to benefit from this program.

What this research studies

This project offers people living with HIV in Cambodia a combined quitting program that includes medicine, counseling, and an automated interactive smartphone messaging system. Participants will be enrolled through local HIV clinics and randomly assigned to the intervention or usual care so researchers can compare outcomes. The messaging app is tailored to each person's smoking patterns and readiness to quit and provides real-time tips and motivation without needing frequent clinic visits. The team has already built the mobile platform and completed a small pilot with 50 participants, and this larger trial will follow people over time to track smoking and health outcomes.

Why it matters

Potential benefit: If successful, the program could help people with HIV in Cambodia stop smoking, improve their overall health, and extend life expectancy.

How similar studies have gone: Combined medication-plus-behavior interventions and mHealth programs have helped smokers in other countries, and the team completed a small pilot with Cambodian PLWH showing feasibility.

Where this research is happening

  • H. Lee Moffitt Cancer Ctr & Res Inst
    Tampa, United States
    Active

Researchers

  • Principal investigator: Vidrine, Damon J. — H. Lee Moffitt Cancer Ctr & Res Inst
  • Study coordinator: Vidrine, Damon J.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.