NIH-funded research R01 grant

Helping breast cancer survivors manage their fear of cancer returning

Official title: Randomized controlled trial of FoRtitude: Targeted eHealth intervention to reduce fear of recurrence among breast cancer survivors in community oncology settings

Funded at Univ of North Carolina Chapel Hill · NIH-10980062 · Data updated 2026-11-12

This study is testing a helpful online program called FoRtitude, designed to support breast cancer survivors in managing their fear of the cancer coming back, using friendly tools and strategies over four weeks.

More Breast Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startAugust 1, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$709,050
NIH project number1R01CA282682-01A1
Project IDNIH-10980062 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are breast cancer survivors experiencing moderate to severe fear of recurrence.

Less likely to help

Patients who are currently undergoing active cancer treatment or those without significant fear of recurrence may not benefit from this research.

What this research studies

This research focuses on developing an eHealth intervention called FoRtitude, aimed at helping breast cancer survivors cope with their fear of recurrence (FoR). The program utilizes cognitive behavioral therapy (CBT) strategies delivered through an online platform, making it accessible and scalable for patients. Participants will engage with interactive tools and didactic content over four weeks, with additional support through motivational interviewing to enhance adherence. The goal is to provide effective coping mechanisms for survivors facing emotional and cognitive challenges after treatment.

Why it matters

Potential benefit: If successful, this research could significantly reduce the fear of cancer recurrence among breast cancer survivors, improving their overall quality of life.

How similar studies have gone: Previous research has shown promising results with similar eHealth interventions for managing psychological distress in cancer survivors.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Wagner, Lynne I. — Univ of North Carolina Chapel Hill
  • Study coordinator: Wagner, Lynne I.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.