Helping American Indian and Alaska Native Communities Address Substance Use Harms

Center for Innovative Research, Capacity Building and Leadership Development to End Substance Use Harms (CIRCLE)

NIH-funded research Johns Hopkins University · NIH-11101273

This center works with American Indian and Alaska Native communities to find new ways to prevent and treat drug and alcohol related health problems.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11101273 on NIH RePORTER

What this research studies

Many American Indian and Alaska Native communities face significant challenges from drug and alcohol use, which can impact their health and lifespan. This center partners directly with these communities to develop new ways to prevent and treat substance use harms. We focus on understanding what causes these issues and what helps people recover, using community-led approaches. Our goal is to find practical solutions and share knowledge to improve health and well-being for these communities.

Who could benefit from this research

Good fit: This center focuses on research and community engagement within American Indian and Alaska Native communities affected by substance use.

Not a fit: Patients outside of American Indian and Alaska Native communities, or those not impacted by substance use harms, may not directly benefit from this specific center's work.

Why it matters

Potential benefit: If successful, this work could lead to more effective prevention and treatment strategies for substance use in American Indian and Alaska Native communities, improving health and longevity.

How similar studies have performed: This center emphasizes Community/Tribally Based Participatory Research, an approach that has shown promise in addressing health disparities in Indigenous communities.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.