NIH-funded research NIH-funded research

Helping Alaska Native people quit smoking using personalized care.

Official title: Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking

Funded at Southcentral Foundation · NIH-10923997 · Data updated 2026-11-12

This study is creating a special program to help Alaska Native and American Indian people quit smoking by using a unique test to tailor the treatment just for them, and we want to see how well this personalized approach works for those trying to quit.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSouthcentral Foundation
NIH-funded
Lab location1 site (Anchorage, United States)
Project startSeptember 24, 2021
Project endJuly 31, 2025
Funding year2024
Award (this year)$339,405
NIH project number5S06GM142122-04
Project IDNIH-10923997 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Alaska Native and American Indian individuals aged 21 and older who are seeking to quit smoking.

Less likely to help

Patients who are not Alaska Native or American Indian, or those who do not smoke, may not benefit from this research.

What this research studies

This research aims to develop a tailored smoking cessation program specifically for Alaska Native and American Indian individuals, who have higher smoking rates compared to other populations. The project will explore the use of a biomarker called nicotine metabolite ratio to personalize treatment options, potentially improving the effectiveness of smoking cessation methods. By assessing the acceptability and feasibility of this approach, the research seeks to enhance existing strategies that have not significantly reduced smoking rates in this community. Participants will be involved in evaluating how well this personalized care can help them quit smoking.

Why it matters

Potential benefit: If successful, this research could lead to more effective smoking cessation treatments for Alaska Native people, ultimately reducing smoking-related health issues.

How similar studies have gone: Previous research has shown promise in using genetically informed biomarkers for smoking cessation in other populations, indicating potential for success in this novel approach.

Where this research is happening

  • Southcentral Foundation
    Anchorage, United States
    Active

Researchers

  • Principal investigator: Michlig, Georgia J — Southcentral Foundation
  • Study coordinator: Michlig, Georgia J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.