NIH-funded research R01 grant

Helping adults with problematic cannabis use sleep better

Official title: Targeting insomnia to improve outcomes in adults with problematic cannabis use

Funded at University of Michigan at Ann Arbor · NIH-11145203 · Data updated 2026-11-12

This project explores how a special type of talk therapy for insomnia can help adults who use cannabis regularly to improve their sleep and reduce cannabis use.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startSeptember 15, 2022
Project endJuly 31, 2027
Funding year2025
Award (this year)$683,594
NIH project number5R01DA057297-04
Project IDNIH-11145203 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults aged 21 and older who experience both insomnia and problematic cannabis use.

Less likely to help

Patients who do not experience insomnia or problematic cannabis use would likely not receive direct benefit from this specific intervention.

What this research studies

Many adults who use cannabis regularly also struggle with insomnia, and sleep problems can make it harder to cut back on cannabis. This project builds on earlier work that showed a tailored talk therapy, called Cognitive Behavioral Therapy for insomnia (CBTi), delivered remotely, helped people sleep better and use less cannabis. We want to understand how this therapy works by looking at the body's natural sleep regulation system. Our goal is to offer a new way to support individuals who want to improve their sleep and manage their cannabis use.

Why it matters

Potential benefit: If successful, this approach could provide an effective, non-medication treatment for insomnia that also helps reduce problematic cannabis use.

How similar studies have gone: A previous pilot trial by this group showed promising results, indicating that a tailored CBTi improved insomnia and reduced cannabis use.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Arnedt, J. Todd — University of Michigan at Ann Arbor
  • Study coordinator: Arnedt, J. Todd

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.