Helping adults with HFpEF stick with regular exercise

HEART Camp Connect: Promoting Adherence to Exercise in Adults with Heart Failure with Preserved Ejection Fraction

NIH-funded research University of Nebraska Medical Center · NIH-11325002

This project compares two support programs to help adults with heart failure with preserved ejection fraction keep up regular moderate exercise long-term.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Medical Center NIH-funded
Lab location1 site (Omaha, United States)
Project IDNIH-11325002 on NIH RePORTER

What this research studies

You would join a randomized trial that assigns adults with HFpEF to one of two exercise-support programs based on the team's earlier HEART Camp approach. The study aims to help people reach and maintain at least 120 minutes per week of moderate-intensity exercise (target heart rate reserve 40–80%). Researchers will follow participants over time to measure exercise adherence, clinical outcomes beyond mortality, and changes in inflammatory blood markers. The team will compare which intervention better promotes long-term exercise and links exercise patterns to clinical and biomarker changes.

Who could benefit from this research

Good fit: Ideal candidates are adults (21+) diagnosed with heart failure with preserved ejection fraction who can safely perform moderate-intensity exercise and commit to follow-up visits.

Not a fit: People without HFpEF, those who cannot exercise safely, or those unwilling to follow the program or attend study visits are unlikely to benefit from participation.

Why it matters

Potential benefit: If successful, this could help people with HFpEF keep exercising and achieve lasting improvements in symptoms, function, and heart health.

How similar studies have performed: The team previously tested the HEART Camp intervention and found it improved long-term exercise adherence in chronic heart failure, with promising subgroup results for HFpEF that now need a larger randomized trial.

Where this research is happening

Omaha, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.