Helping adults at higher risk get retested for HIV more often

Transformative approaches to rapidly and efficiently test demand creation interventions to promote HIV retesting in adults at increased risk of HIV

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11415858

This project tries out simple nudges—like reminders, prompts, and small incentives—to help adults at higher HIV risk in sub‑Saharan Africa retest more often.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11415858 on ClinicalTrials.gov

What this research studies

You and other community members will help adapt low‑cost behavioral nudges so they fit local situations and address barriers like stigma, time costs, and misunderstandings about testing. The team will use participatory prototyping with patients and providers to tailor reminders, prompts, or small incentives to encourage retesting. A large randomized "mega‑trial" will then assign individuals to many different nudge options to see which ones most increase retesting. The work focuses on adults at increased HIV risk in sub‑Saharan Africa and connects retesting to faster diagnosis and better access to prevention like PrEP.

Who could benefit from this research

Good fit: Adults (age 21 and older) who are at increased risk of HIV and who live near participating sites in sub‑Saharan Africa are the ideal candidates.

Not a fit: Children, people not at increased HIV risk, or those living outside the study areas or unwilling to follow trial procedures are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this could lead to more timely HIV diagnoses and quicker access to treatment or prevention, reducing illness and onward transmission.

How similar studies have performed: Behavioral nudges have improved health behaviors in past studies, but using a large multi‑arm trial to find the best nudges for HIV retesting is relatively new.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.