NIH-funded research U01 cooperative agreement

Help for young people with HIV in Zambia to find and complete cancer care

Official title: Integrated delivery of cancer control interventions for adolescents and young adults living with HIV in Zambia

Funded at Implenomics Llcs · NIH-11174224 · Data updated 2026-11-12

This program aims to help teenagers and young adults living with HIV in Zambia get cancers found earlier and receive support to complete cancer treatment using peer counselors, clinician learning networks, and health-system coordination.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionImplenomics Llcs
NIH-funded
Lab location1 site (Marblehead, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2027
Funding year2025
Award (this year)$751,227
NIH project number5U01CA275054-04
Project IDNIH-11174224 on NIH RePORTER

Who could benefit from this research

Could help

Teenagers and young adults living with HIV in Zambia who receive care at participating clinics and are at risk for Kaposi sarcoma, non-Hodgkin lymphoma, or cervical cancer are the ideal candidates.

Less likely to help

People who live outside Zambia, are not treated at participating sites, or who have unrelated cancer types or non-HIV conditions are unlikely to benefit directly from this program.

What this research studies

If I'm a young person living with HIV in Zambia, this program would place trained peer counselors in clinics to help me spot cancer signs, keep appointments, and stick with treatment. It would also create peer-to-peer learning networks so HIV and cancer clinicians share knowledge and coordinate care. Health administrators and Ministry of Health leaders would work together to remove system barriers and try joint solutions. The project will compare the ARROW program to current practice using implementation science methods and look at outcomes, how well the program is put into routine care, and its costs.

Why it matters

Potential benefit: If successful, the program could catch cancers earlier and increase the number of young people who complete recommended cancer treatment, lowering preventable deaths.

How similar studies have gone: Peer support and provider-learning networks have helped engagement and screening in HIV and some cancer programs elsewhere, but combining these approaches specifically for adolescents and young adults with HIV is relatively new.

Where this research is happening

  • Implenomics Llcs
    Marblehead, United States
    Active

Researchers

  • Principal investigator: Subramanian, Sujha — Implenomics Llcs
  • Study coordinator: Subramanian, Sujha

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.