HeartShare: Understanding Different Types of Heart Failure and Their Treatments
HeartShare: Next-Generation Phenomics to Define Heart Failure Subtypes and Treatment Targets - Clinical Centers
This project is gathering detailed health information from people with heart failure to better understand different types of the condition and find new ways to help them.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11158829 on NIH RePORTER |
What this research studies
Heart failure with preserved ejection fraction (HFpEF) affects many people and is very complex, making it challenging to find effective treatments. Researchers believe that HFpEF isn't just one condition but many different types, each potentially needing a specific approach. This project plans to collect extensive health data from 1000 patients, including those with HFpEF, other forms of heart failure, and a control group with high blood pressure. By looking closely at clinical details, social factors, quality of life, and physical activity, we hope to uncover distinct patient groups. This deep understanding could lead to personalized treatments that work better for each specific type of heart failure.
Who could benefit from this research
Good fit: Ideal candidates include adults aged 21 and older with heart failure (both HFpEF and HFrEF) or high blood pressure without heart failure.
Not a fit: Patients who do not have heart failure or high blood pressure, or who are under 21 years old, would not directly benefit from participating in this specific data collection.
Why it matters
Potential benefit: If successful, this work could lead to more personalized and effective treatments for different types of heart failure, particularly for those with heart failure with preserved ejection fraction (HFpEF).
How similar studies have performed: Previous work by this group and others has shown that thoroughly studying patient characteristics can help identify different subgroups of heart failure, suggesting this approach is promising.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Chirinos Medina, Julio Alonso — University of Pennsylvania
- Study coordinator: Chirinos Medina, Julio Alonso
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.