Heart Health and Using Both Cigarettes and E-cigarettes

Cardiovascular Effects of Inhalable Tobacco Product Dual Use

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11192277

This project looks at how using both traditional cigarettes and e-cigarettes might affect your heart and blood vessels.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11192277 on ClinicalTrials.gov

What this research studies

For a long time, e-cigarettes were thought to be a safer choice than traditional cigarettes, but we are learning that they can also harm your heart. This project explores how e-cigarettes, heated tobacco products, and traditional cigarettes individually affect your cardiovascular system. We also want to understand if using both cigarettes and e-cigarettes at the same time could cause even more harm. The goal is to identify the specific ways these products impact heart health, even beyond nicotine's effects.

Who could benefit from this research

Good fit: This foundational research is not directly recruiting patients but focuses on understanding the cardiovascular effects of tobacco products, which is relevant to individuals who use or have used cigarettes and e-cigarettes.

Not a fit: Patients who have never used tobacco products or e-cigarettes may not directly benefit from this specific research, as it focuses on the effects of these products.

Why it matters

Potential benefit: If successful, this work could help us better understand the risks of using tobacco products, especially when combining e-cigarettes and traditional cigarettes, leading to better public health guidance.

How similar studies have performed: Previous research by this group and others has shown that both e-cigarettes and traditional cigarettes can cause adverse cardiovascular effects, and this project builds on that existing knowledge.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.