Heart health and pregnancy outcomes

The Heart Outcomes for Pregnancy Expectations Study

NIH-funded research University of Missouri Kansas City · NIH-11195055

This project follows pregnant people with heart disease to see which care setups and patient traits link to better outcomes for mothers and babies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Missouri Kansas City NIH-funded
Lab location1 site (Kansas City, United States)
Project IDNIH-11195055 on NIH RePORTER

What this research studies

You would be one of 1,000 pregnant people with cardiovascular disease seen across 33 cardio-obstetrics clinics in the United States. Doctors will collect medical records, symptoms and quality-of-life questionnaires, and information about how each clinic is organized. The study will track pregnancy complications, maternal heart events, and newborn problems over time. By comparing patients and clinic features, the team hopes to find which care components relate to better or worse outcomes.

Who could benefit from this research

Good fit: People who are pregnant and have known or newly diagnosed cardiovascular disease who start prenatal care at one of the participating cardio-obstetrics clinics.

Not a fit: People without cardiovascular disease during pregnancy are unlikely to receive direct benefit from this study.

Why it matters

Potential benefit: If successful, the results could point to clinic setups and care strategies that reduce pregnancy complications and heart-related maternal deaths.

How similar studies have performed: Smaller clinic reports and expert recommendations exist, but this is the first large, US-based prospective study testing which cardio-obstetrics care components link to outcomes.

Where this research is happening

Kansas City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.