Heart failure with preserved ejection fraction in California's Central Valley
A prospective multiethnic HFpEF cohort from California's Central Valley
This project looks at organ-specific metabolism and inflammation in people with HFpEF from California's Central Valley to find patterns that could guide better care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11420037 on NIH RePORTER |
What this research studies
You would join a long-term group of patients with HFpEF from the Central Valley where doctors will collect detailed medical records, wearable/mobile health data, blood samples, and advanced imaging as part of deep phenotyping. The team will use a new total-body PET scanner at UC Davis to measure organ-specific metabolism and inflammation and apply functional connectomics to map how organ systems interact. Researchers will combine electronic health records, web portals, and direct-to-participant contact to follow symptoms and outcomes over time. The study emphasizes enrolling a diverse, multiethnic population with a large representation of Latino patients from the region.
Who could benefit from this research
Good fit: Adults diagnosed with heart failure with preserved ejection fraction (HFpEF) who live in or near California's Central Valley and can travel to UC Davis or affiliated clinics are ideal candidates.
Not a fit: People without HFpEF, those with reduced ejection fraction heart failure, or those unable to travel to study sites are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, it could point to personalized treatments or new biological targets for people with HFpEF.
How similar studies have performed: Previous research has shown HFpEF is a heterogeneous condition, but combining total-body PET imaging with functional connectomics in a large multiethnic cohort is largely novel.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Chiamvimonvat, Nipavan — University of California at Davis
- Study coordinator: Chiamvimonvat, Nipavan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.