Heart and lung health after tuberculosis
Heart and Lung Outcomes Post-TB (HALO Post-TB)
This project looks at lung and heart health in people who have had tuberculosis, including those living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11193953 on NIH RePORTER |
What this research studies
If I join, researchers will perform full breathing tests (including how well oxygen passes into my blood), heart ultrasound scans, and exercise tests to measure fitness. They will collect blood samples and other data and repeat key tests over time to see how my heart and lungs change after TB. The team will compare people with and without HIV to understand whether HIV changes the pattern of lasting problems. The goal is to find who has lasting lung or heart damage and the biological reasons behind it.
Who could benefit from this research
Good fit: People who previously had pulmonary tuberculosis and are able to attend clinic visits and testing, including those living with HIV, would be ideal candidates.
Not a fit: People without a history of tuberculosis or those unable or unwilling to undergo repeated clinic tests and procedures are unlikely to benefit directly from participation.
Why it matters
Potential benefit: If successful, this work could help doctors detect and manage long-term lung and heart problems after TB, especially for people with HIV.
How similar studies have performed: Earlier studies have linked HIV with worse lung and heart test results, but combining full lung function testing, heart imaging, and exercise testing specifically after TB is relatively new.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Hsue, Priscilla Y. — University of California Los Angeles
- Study coordinator: Hsue, Priscilla Y.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.