Healing the immune system after radiation exposure
Official title: Regeneration of the Immune System after Radiation Exposure
Funded at Albert Einstein College of Medicine · NIH-10873791 · Data updated 2026-11-12
This study is looking at how radiation affects your immune system and how your body can heal itself afterward, specifically for people who have had radiation exposure, like those with acute radiation syndrome or its delayed effects.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | August 18, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $582,293 |
| NIH project number | 5U01AI170032-03 |
| Project ID | NIH-10873791 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have suffered from acute radiation syndrome or have been exposed to significant levels of radiation.
✕Less likely to help
Patients who have not been exposed to radiation or who do not exhibit symptoms of immune dysfunction may not benefit from this research.
What this research studies
This research investigates how radiation exposure affects the immune system and aims to understand the regeneration process of immune cells in the body. It focuses on patients who have experienced acute radiation syndrome or delayed effects from radiation, examining the immune landscape in various organs such as the bone marrow, spleen, and intestines. The study will analyze the functionality of immune cells and the overall recovery of the immune system after radiation damage, using advanced methodologies to assess immune responses and cell regeneration.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance immune recovery in patients exposed to radiation.
How similar studies have gone: Previous research has shown promising results in understanding immune recovery after radiation exposure, indicating that this approach has potential for success.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Guha, Chandan — Albert Einstein College of Medicine
- Study coordinator: Guha, Chandan
Related research
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-
Restoring bone marrow blood vessels to prevent delayed radiation damage
This project aims to help people exposed to acute radiation by repairing the bone marrow’s blood vessel network to support healthier blood cell recovery over time.
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Raman-based quick triage for radiation exposure
A new approach uses Raman spectroscopy and AI to quickly estimate radiation dose in people exposed to a radiological event, helping doctors decide who needs urgent treatment.
-
ACE2-agonist to reduce long-term radiation damage after ARS
Aims to test an ACE2-activating drug (diminazene aceturate) to lessen long-term organ damage after acute radiation exposure in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.