NIH-funded research Sbir 2 grant

Handheld device to help COPD patients breathe better

Official title: Portable Noninvasive Positive Airway Device for COPD Patient Therapy

Funded at Koronis Biomedical Technologies Corporat · NIH-10675430 · Data updated 2026-11-12

This study is testing a small, easy-to-use device that helps people with COPD breathe better when they're feeling short of breath, so they can feel more comfortable and confident doing everyday activities.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionKoronis Biomedical Technologies Corporat
NIH-funded
Lab location1 site (Minneapolis, UNITED STATES)
Project startAugust 15, 2020
Project endJuly 31, 2025
Funding year2023
Award (this year)$940,209
NIH project number5R44HL154932-03
Project IDNIH-10675430 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Chronic Obstructive Pulmonary Disease (COPD) who experience exertional dyspnea.

Less likely to help

Patients with mild or no symptoms of COPD may not receive significant benefit from this research.

What this research studies

This research focuses on developing a portable, handheld device that provides bi-level positive airway pressure (BiPAP) therapy for patients with Chronic Obstructive Pulmonary Disease (COPD) who experience breathlessness during daily activities. The device aims to alleviate acute dyspnea, allowing patients to engage more confidently in their everyday lives. By optimizing the BiPAP therapy in a miniaturized form, it seeks to break the cycle of inactivity and fear associated with breathing difficulties. Patients will be able to use this device on the go, enhancing their functional capacity and overall quality of life.

Why it matters

Potential benefit: If successful, this research could significantly improve the quality of life for COPD patients by enabling them to manage their breathing difficulties more effectively.

How similar studies have gone: Previous research has shown success with similar portable respiratory devices, indicating a promising avenue for improving COPD management.

Where this research is happening

  • Koronis Biomedical Technologies Corporat
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Knuesel, Robert J — Koronis Biomedical Technologies Corporat
  • Study coordinator: Knuesel, Robert J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.