Guiding Anticoagulation Choices for Atrial Fibrillation in Long-Term Care

Who could benefit from this research

What this research studies

Older adults with atrial fibrillation often need ongoing reassessment of their blood thinner therapy when they move into long-term care. The project plans to use real-world health data from linked electronic records and Medicare data to compare continuing, stopping, or starting anticoagulants at LTC admission. It will build and validate models to predict who benefits most from therapy changes and develop a user-friendly decision aid for clinicians and patients. The work focuses on improving personalized care during a critical health transition to reduce both stroke and bleeding harms.

Why it matters

Where this research is happening

• Hebrew Rehabilitation Center for Aged
  Boston, United States Active

Researchers

• Principal investigator: Ko, Darae — Hebrew Rehabilitation Center for Aged
• Study coordinator: Ko, Darae

Related research

Other NIH-funded projects on the same topics.

• Cardiomyocyte-fibroblast signaling in atrial fibrillation

  A researcher at Baylor College of Medicine is studying how signals between heart muscle cells and supportive heart cells influence atrial fibrillation, with the goal of finding new ways to prevent or treat this common heart rhythm problem.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11617730

• Anticoagulation in ICH Survivors with Atrial Fibrillation and Small Vessel Disease

  This project looks at how to safely use blood-thinning medicines in people who survived a brain bleed and also have atrial fibrillation and small vessel disease.

  NIH research Yale University · New Haven, United States · NIH-11533213

• Lowering heart inflammation to reduce atrial fibrillation risk in people with diabetes

  Seeing whether blocking a pro-inflammatory enzyme or boosting the heart's natural inflammation-resolving signals can lower atrial fibrillation risk in people with diabetes.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11512008

• Atrial fibrillation, clots, and stroke: the heart’s JNK2 as a target

  This NIH grant explores how a heart protein called JNK2 may drive atrial fibrillation, blood clots, and stroke, and whether it could serve as a biomarker and new treatment approach.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11465511

• A risk score to spot high-risk heart failure patients without atrial fibrillation who may need anticoagulation

  A new tool uses patient data and heart MRI markers to identify heart failure patients without atrial fibrillation who might benefit from anticoagulation while minimizing bleeding risk.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11451573

• DECIDE-AF: a shared decision tool in your health portal to help prevent strokes in atrial fibrillation

  A patient-friendly tool in your electronic health record helps you and your doctor choose the right way to prevent strokes if you have atrial fibrillation.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11450366

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.