Guidelines for safely reducing benzodiazepine use

National Practice Guidelines for Safe Tapering of Benzodiazepines

NIH-funded research American Society of Addiction Medicine · NIH-10676509

This study is working on creating helpful guidelines for doctors on how to safely reduce benzodiazepine medications, which are often used for anxiety and sleep issues, especially for older adults, to make sure they can do it without causing withdrawal problems or other risks.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionAmerican Society of Addiction Medicine NIH-funded
Lab location1 site (Rockville, United States)
Project IDNIH-10676509 on NIH RePORTER

What this research studies

This research focuses on developing national guidelines for the safe tapering of benzodiazepine medications, which are often prescribed for conditions like anxiety and insomnia. The project aims to address the risks associated with benzodiazepine withdrawal and overdose, particularly in vulnerable populations such as older adults. By establishing clear protocols for tapering, the research seeks to help clinicians manage the complex process of reducing benzodiazepine dosages while minimizing withdrawal symptoms and the risk of relapse. The methodology includes reviewing existing literature and clinical practices to create evidence-based recommendations.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients currently prescribed benzodiazepines who may need to taper their medication safely.

Not a fit: Patients who are not currently using benzodiazepines or those who are not experiencing adverse effects from their use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide healthcare providers with essential guidelines to safely taper benzodiazepine medications, reducing the risk of withdrawal and overdose for patients.

How similar studies have performed: While there is limited research specifically on tapering benzodiazepines, similar approaches in managing other medications have shown success in establishing safe guidelines.

Where this research is happening

Rockville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.